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Structure of DNA and how it copies itself sheet
5-mark answer frame

Explain, with a labelled diagram, how one DNA molecule gives rise to two identical molecules before a cell divides. Say what DNA is made of, including its four bases.

How to lay out the answer. Follow the frame, then write it in your own words.

  1. 1 · Define. DNA replication is the copying of one DNA molecule into two identical molecules before a cell divides.
  2. 2 · Say why it is needed. Each daughter cell must get the same number of identical chromosomes.
  3. 3 · Describe the structure. DNA is a double helix of two strands of nucleotides; each nucleotide is a base + deoxyribose sugar + phosphate.
  4. 4 · Name the bases. Adenine, guanine, thymine and cytosine.
  5. 5 · Write the steps.
    • Enzymes unwind the double helix and expose the two strands.
    • DNA polymerase builds a new daughter strand along each old strand.
    • Two DNA molecules form, each with one old and one new strand; they become two chromatids joined at the centromere.
  6. 6 · Draw it. [Diagram: double helix opening into a Y; new strands along each old strand; two daughter double helices; labels: parent strand, new strand, DNA polymerase, bases]
  7. 7 · Close in one line. So every new cell gets an exact copy of the DNA.

Scoring tip: Number the three steps and label the old and new strands in the diagram; the labels carry marks.