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Unit II · Muscle physiology and energy systems
10 min readPathway sheetVery often a 10-mark answer with a diagram

Energy systems for exercise: ATP-PC, glycolytic and oxidative

Muscle runs only on ATP. Three systems rebuild it: ATP-PC for about 10 seconds, glycolysis up to about 2 minutes, and the oxidative system beyond that.

Stored ATPLasts only about 2-3 seconds of all-out effort
ATP-PC (phosphagen)Up to about 10 s; PCr + ADP → ATP + creatine (creatine kinase)
Anaerobic glycolysisAbout 10 s to 2 min; net 2 ATP per glucose; lactate formed
Oxidative systemBeyond about 2 min; about 30-32 ATP per glucose (older books give 36-38)

The energy continuum

All three systems work at the same time. Intensity and duration decide which one leads.

Comparison of the three energy systems

FeatureATP-PCAnaerobic glycolysisOxidative
Oxygen neededNoNoYes
FuelPhosphocreatineGlucose and muscle glycogenCarbohydrate, fat, a little protein
SiteCytoplasmCytoplasmMitochondria
Rate of ATP supplyFastestFastSlowest
CapacityVery smallLimitedVery large
ATP yield1 ATP per PCrNet 2 per glucose (3 per glucose unit from glycogen)About 30-32 per glucose; about 106 per palmitate
By-productsCreatineLactate and hydrogen ionsCarbon dioxide and water
Leads in efforts ofUp to about 10 sAbout 10 s to 2 minBeyond about 2 min
RecoveryPCr about half restored in 30 s, nearly full in a few minutesLactate mostly cleared within about an hour; sooner with an easy cool-downNot limited by a store
Sport examples100 m, shot put, javelin, high jump, a fast bowler's delivery400 m, 100 m swim, a 30-second kabaddi raidMarathon, 10,000 m, road cycling, a full hockey match

Key reactions

  1. 1
    ATP → ADP + Pi + energy for the cross-bridge stroke.
    ATPase
  2. 2★
    PCr + ADP → ATP + creatine: the fastest way to rebuild ATP.
    Creatine kinase
  3. 3
    ADP + ADP → ATP + AMP: a small backup when ADP piles up.
    Myokinase (adenylate kinase)
  4. 4★
    Glucose → 2 pyruvate + net 2 ATP + 2 NADH in the cytoplasm.
    Phosphofructokinase is the rate-limiting enzyme
  5. 5
    Pyruvate → lactate when pyruvate is made faster than mitochondria can use it; this regenerates NAD+ so glycolysis can continue.
    Lactate dehydrogenase
  6. 6★
    Pyruvate → acetyl-CoA → Krebs cycle → electron transport chain → ATP, CO2 and water, in the mitochondria.
  7. 7
    Fatty acids → beta-oxidation → acetyl-CoA → Krebs cycle: slow, needs oxygen, but gives a very large ATP yield.

★ one-way, controls the pace

Energy systems in Indian sports

SportMain systemsDiet focus
Sprints, shot put, javelin, weightliftingATP-PCProtein, enough carbohydrate, creatine stores
KabaddiATP-PC and glycolysis in each raid; oxidative between raidsCarbohydrate for repeated efforts, protein, fluids
Hockey and footballAll three (stop-and-start)High carbohydrate, fluids, recovery snacks
Cricket fast bowlingATP-PC for each ball; oxidative over a long spellCarbohydrate and fluid spread across the day
400 m and 800 mGlycolysis with a large oxidative shareFull glycogen; buffers such as beta-alanine or bicarbonate
Marathon and long-distanceOxidativeCarbohydrate loading, carbohydrate during the race, fluids
For the athlete

The energy system shapes the diet: ATP-PC athletes (throwers, sprinters) benefit from creatine stores and protein, glycolytic events need full glycogen and buffering, and oxidative events need carbohydrate loading, carbohydrate during the race and fluids. Vegetarian athletes have lower muscle creatine, since food creatine comes mainly from meat and fish.

Exam angle

2 marks: “What is the phosphagen (ATP-PC) system?” PCr gives its phosphate to ADP to rebuild ATP (creatine kinase). It needs no oxygen and powers maximal efforts of up to about 10 seconds.

5 marks: “Compare the aerobic and anaerobic energy systems.” Table of oxygen use, fuel, site, rate, capacity, ATP yield, by-products, duration and sport examples.

10 marks: “Explain the energy systems used during exercise with a neat diagram. Give sports examples for each.” Energy continuum diagram, then each system's reaction, rate, capacity, yield, duration and examples, a comparison table and a diet note.

Remember it

10 seconds, 2 minutes, beyond: PCr powers the sprint, glycolysis the 400 m, oxygen the marathon.