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Unit II · Diseases of the gastrointestinal tract
9 min readConcept sheetOften a 10-mark answer; 'UC vs Crohn's' is a common 5-mark question

Inflammatory bowel disease: ulcerative colitis and Crohn's disease

IBD is chronic, relapsing inflammation of the gut: ulcerative colitis in the colon, Crohn's anywhere from mouth to anus. In a flare, give enough energy, high protein, low residue.

Two typesUlcerative colitis (UC) and Crohn's disease
Energy in a flareAbout 30-35 kcal/kg (textbook figure; ESPEN says needs are usually like a healthy person's)
Protein in a flareAbout 1.2-1.5 g/kg; about 1 g/kg in remission (ESPEN)
Children with Crohn'sExclusive enteral nutrition (formula only) for 6-8 weeks can induce remission

At a glance

DefinitionA group of chronic diseases with relapsing and remitting inflammation of the intestine, caused by an abnormal immune response
CausesGenes, an over-active immune response to gut bacteria, environment (refined Western diet, antibiotics); smoking worsens Crohn's disease
SymptomsDiarrhoea (bloody in UC), abdominal pain, urgency, fever, fatigue, loss of appetite, weight loss; growth failure in children
Nutrition problemsWeight and muscle loss, anaemia (iron, B12, folate), protein loss, dehydration, low calcium and vitamin D (steroids), low zinc

Ulcerative colitis vs Crohn's disease

FeatureUlcerative colitisCrohn's disease
SiteColon and rectum only, starting at the rectumAny part from mouth to anus; most often the end of the ileum
PatternContinuous inflammationPatchy 'skip lesions' with normal gut between
DepthInner lining (mucosa) onlyWhole thickness of the wall (transmural)
StoolsBloody diarrhoea with mucus, urgencyDiarrhoea and cramping pain, less blood
ComplicationsSevere bleeding, toxic megacolon, raised colon cancer riskStrictures, fistulas, abscesses, malabsorption, B12 deficiency, kidney stones

Dietary principles

NutrientIn a flareIn remission
EnergyEnough to stop weight loss: about 30-35 kcal/kg (textbooks; ESPEN: usually like a healthy person's), small frequent mealsNormal, to keep a healthy weight
ProteinHigh: about 1.2-1.5 g/kg (egg, fish, chicken, paneer, curd, soft dal)About 1 g/kg
FatModerate; low if fat is not absorbed (steatorrhoea); MCT oil helpsNormal
FibreLow residue during flares and when there are stricturesIncrease slowly; whole fruits and vegetables as tolerated
LactoseLimit milk if intolerant; curd is usually toleratedAs tolerated
Fluid and electrolytesExtra fluids, ORS if diarrhoea is heavyNormal
MicronutrientsIron, folate, B12 (injections if the ileum is affected), calcium, vitamin D, zincCheck blood levels regularly

Foods to include and avoid, and a sample menu (flare)

ItemDetails
IncludeSoft rice, idli, rava upma, refined-flour chapati, moong dal, egg, steamed fish, chicken stew, paneer, curd, peeled cooked vegetables, banana, papaya, stewed apple
Avoid during a flareWhole grains with bran, whole pulses, raw salads, skins and seeds, nuts, popcorn, fried foods, spicy curries, alcohol, sugary drinks
Early morningOral nutrition supplement or milkshake made with lactose-free milk
BreakfastIdli (3) with moong dal; boiled egg
Mid-morningRipe banana; curd
LunchSoft rice, fish stew (mild), mashed carrot-potato, curd
EveningRava upma with peeled vegetables; buttermilk
DinnerSoft chapati (refined flour), paneer bhurji (mild), bottle gourd curry
BedtimeCustard or a supplement drink
At the bedside

On the ward, weigh IBD patients twice a week; weight loss is often hidden by fluid shifts. Patients with strictures must stay on low-residue food to avoid a blocked bowel, and those with ileal disease usually need B12 injections.

Exam angle

2 marks: “What are skip lesions?” Patches of diseased bowel separated by normal bowel; typical of Crohn's disease.

5 marks: “Differentiate ulcerative colitis and Crohn's disease.” Site, pattern, depth, stools and complications in a five-row table.

10 marks: “Discuss the dietary management of inflammatory bowel disease.” Define IBD, UC vs Crohn's, causes, symptoms, nutrition problems, principles table for flare and remission, foods and a flare menu.

Remember it

UC = Unbroken Colon (continuous, colon only). Crohn's = Can be anywhere, Chunks skipped.