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Unit III · Liver, gall bladder and fevers
9 min readConcept sheetOften a 10-mark answer; metabolic changes in fever come as a 5-mark note

Fever: metabolic changes, and typhoid

Fever raises BMR by about 13% for every 1 °C, breaks down protein and drains fluid. Typhoid needs a high-calorie, high-protein, low-residue, high-fluid diet.

FeverBody temperature above normal (about 37 °C or 98.6 °F)
BMR in feverRises about 13% per 1 °C (about 7% per 1 °F)
TyphoidCaused by Salmonella Typhi; spread by contaminated food and water
FluidAt least 2.5-3 litres a day, more with sweating or diarrhoea

At a glance

Types of fever by durationAcute (short, high: influenza, malaria, typhoid) and chronic (long, low-grade: tuberculosis)
Types by patternContinuous (stays high, e.g. typhoid), intermittent (comes and goes to normal, e.g. malaria), remittent (rises and falls but never reaches normal)
Metabolic changesBMR up about 13% per 1 °C; faster use of glycogen; protein breakdown and negative nitrogen balance; water and salt lost in sweat; poor appetite; higher need for B vitamins, vitamins A and C
Typhoid: causeSalmonella Typhi (paratyphoid: S. Paratyphi) from contaminated food, water and carriers
Typhoid: symptomsFever rising step by step over the first week, headache, weakness, coated tongue, abdominal pain, constipation or diarrhoea, rose-coloured spots, enlarged spleen
Typhoid: complicationsUlcers in the Peyer's patches of the ileum can bleed or perforate in the second or third week

Worked example: energy needs in fever

Problem

A woman normally needs 2,000 kcal a day. She has typhoid with a temperature of 39 °C. How much energy does she need?

Working
  1. Normal temperature = 37 °C, so the rise = 39 − 37 = 2 °C.
  2. BMR rises about 13% per 1 °C, so the increase = 13% × 2 = 26%.
  3. Extra energy = 26% of 2,000 = 0.26 × 2,000 = 520 kcal.
  4. Total = 2,000 + 520 = 2,520 kcal, rounded to about 2,500 kcal.
Answer

About 2,500 kcal a day (2,520 kcal before rounding). In °F, use about 7% per 1 °F rise.

Dietary principles in typhoid

NutrientRecommendationWhy
EnergyHigh: add about 13% per 1 °C rise; easily digested carbohydrate (glucose, sugar, kanji, rice)Fever raises BMR; carbohydrate spares protein
ProteinHigh: about 1-1.5 g/kg (textbook range) from milk, curd, egg, soft dal, paneerReplaces protein lost in negative nitrogen balance
FatModerate, in emulsified form (milk, butter, cream)Adds energy; heavy fried fat is poorly tolerated
FibreLow residue: no whole grains, skins, seeds or raw saladsProtects the ulcerated ileum from bleeding and perforation
Fluid and electrolytes2.5-3 litres or more: ORS, tender coconut water, juices, soups, buttermilk with saltReplaces loss from sweat and diarrhoea
Meal pattern and textureLiquid to soft, bland food in small feeds every 2-3 hoursEasy on a weak appetite and inflamed gut

Foods and a sample one-day menu (typhoid)

ItemDetails
IncludeMilk, curd, buttermilk, egg, soft rice, rice kanji, idli, custard, mashed potato, boiled and strained vegetables, banana, papaya, fruit juices, glucose
AvoidWhole grains, whole pulses, raw salads, fruits with skins and seeds, fried foods, chilli and spices, pickles, street food
6 amMilk with sugar or glucose
8 amIdli (3) with dal; boiled egg
10 amSweet lime juice or tender coconut water
12 noonSoft rice with dal, mashed potato, curd
3 pmCustard or milkshake
5 pmRice kanji with salt; banana
8 pmCurd rice; strained vegetable soup
10 pmWarm milk
At the bedside

In a fever ward, record the temperature with each feed: as the fever rises, energy and fluid needs rise. Typhoid patients feel hungry in the third week, but high-fibre food must wait until the gut ulcers heal.

Exam angle

2 marks: “How much does BMR rise in fever?” About 13% for every 1 °C rise in body temperature (about 7% per 1 °F).

5 marks: “Explain the metabolic changes in fever.” Higher BMR, faster glycogen use, protein breakdown and negative nitrogen balance, water and salt loss, poor appetite, higher vitamin needs.

10 marks: “Discuss the dietary management of typhoid fever with a one-day menu.” Cause, symptoms and complications, metabolic changes, energy calculation, principles table (high energy, protein, fluid; low residue; bland), foods, menu.

Remember it

Fever diet = H-H-H-L: High calorie, High protein, High fluid, Low residue. 13% per degree Celsius.