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Unit IV · Metabolic disorders
10 min readConcept sheetGI, GL and sweeteners come as 2- and 5-mark questions

Glycaemic index, glycaemic load, carbohydrate counting and artificial sweeteners

GI shows how fast a food raises blood sugar; GL adds how much carbohydrate a serving holds. Carbohydrate counting and sweeteners help diabetics plan meals and insulin.

GI cut-offsLow 55 or less; medium 56-69; high 70 or more (glucose = 100)
Glycaemic loadGL = GI × available carbohydrate (g) per serving ÷ 100; low 10 or less, high 20 or more
One carb choice15 g carbohydrate
WHO (2023)Advises against using non-sugar sweeteners for weight control (the advice does not cover people who already have diabetes)

GI vs GL

Glycaemic index (GI)The rise in blood glucose over 2 hours after eating a food with 50 g available carbohydrate, compared with 50 g of glucose (GI 100). It ranks the quality of carbohydrate: low 55 or less, medium 56-69, high 70 or more.
Glycaemic load (GL)GL = GI × grams of available carbohydrate in the serving ÷ 100. It combines quality and quantity, so it predicts the real effect of a normal portion: low 10 or less, medium 11-19, high 20 or more.

GI values change with variety, ripeness and cooking, so use them to compare foods, not as exact numbers.

What changes GI, with Indian examples

FactorEffectExample
Type of starchMore amylose, lower GIParboiled rice tends to have a lower GI than polished raw rice
Processing and cookingGrinding, flaking, puffing and overcooking raise GIPuffed rice and cornflakes are high; whole grains and dalia are lower
FibreSoluble fibre lowers GIOats, barley, pulses, methi seeds
Fat, protein and acid in the mealSlow stomach emptying, lower GIRice with dal and curd raises sugar less than plain rice
RipenessRiper fruit, higher GIRipe banana is higher than a firm one
Cooling cooked starchForms resistant starch, lowers GI a littleCooled rice in curd rice
Low-GI foodsRaise blood sugar slowlyMost pulses (rajma, chana, moong), milk, curd, apple, orange, guava, barley
High-GI foodsRaise blood sugar fastGlucose, white bread, cornflakes, puffed rice, mashed potato, many polished rice varieties

Worked example 1: glycaemic load

Problem

Watermelon has a high GI (about 72 in the international GI tables), but a 120 g serving has only about 6 g carbohydrate. Cooked white rice has a GI of about 73, and a 150 g serving has about 42 g carbohydrate. Find the GL of each.

Working
  1. Watermelon: GL = 72 × 6 ÷ 100 = 432 ÷ 100 = 4.3 (low).
  2. White rice: GL = 73 × 42 ÷ 100 = 3,066 ÷ 100 = 30.7 (high).
  3. Both foods have almost the same GI, but the rice serving carries seven times more carbohydrate.
Answer

Watermelon GL about 4 (low); white rice GL about 31 (high). Portion size matters as much as GI.

Worked example 2: carbohydrate counting

Problem

A type 1 diabetic on rapid-acting insulin eats 2 phulkas (30 g atta each), 1 bowl dal (30 g raw), 100 g vegetables and 100 mL curd. Count the carbohydrate and carb choices. Use the exchange values: cereal 20 g, pulse 18 g, vegetable 5 g, curd 5 g carbohydrate.

Working
  1. Phulkas: 2 × 20 g = 40 g.
  2. Dal: 18 g. Vegetables: 5 g. Curd: 5 g.
  3. Total = 40 + 18 + 5 + 5 = 68 g carbohydrate.
  4. Carb choices = 68 ÷ 15 = 4.5, about 4½ choices.
  5. Record the count: the doctor uses it, with the patient's own insulin-to-carbohydrate ratio, to set the meal-time insulin. The dietitian counts; the doctor decides the dose.
Answer

68 g carbohydrate, about 4½ carb choices. The doctor uses this count to set the meal-time insulin.

Artificial (non-nutritive) sweeteners

SweetenerSweetness vs sugarEnergyNotes
SaccharinAbout 300-500 timesNoneHeat-stable; bitter aftertaste; ADI 5 mg/kg body weight
AspartameAbout 200 times4 kcal/g, but used in tiny amountsLoses sweetness on heating; contains phenylalanine, so labelled for people with phenylketonuria (PKU); ADI 40 mg/kg; IARC (2023) called it possibly carcinogenic but JECFA kept the ADI
Acesulfame-KAbout 200 timesNoneHeat-stable; often blended with aspartame; ADI 15 mg/kg
SucraloseAbout 600 timesNoneMade from sugar; heat-stable, used in cooking and baking; ADI 15 mg/kg
Steviol glycosides (stevia)About 200-300 timesNoneFrom the stevia plant; heat-stable; ADI 4 mg/kg (as steviol)
Sugar alcohols (sorbitol, mannitol, xylitol)Half to equalAbout 1.6-2.6 kcal/gIn sugar-free sweets and gum; excess causes gas and diarrhoea
At the bedside

In the diabetes clinic, teach swaps by GL, not just GI: a small serving of watermelon is fine, a large plate of white rice is not. Sweeteners can replace sugar in tea, but WHO (2023) does not advise them for weight loss, and they do not make sweets or bakery items safe.

Exam angle

2 marks: “Define glycaemic index.” The blood-glucose rise over 2 hours after a food with 50 g available carbohydrate, compared with 50 g glucose (GI 100). Low 55 or less; high 70 or more.

5 marks: “Write a note on artificial sweeteners.” Define, then saccharin, aspartame, acesulfame-K, sucralose, stevia and sugar alcohols with sweetness, energy, heat stability, ADI, PKU warning and WHO 2023 advice.

10 marks: “Explain glycaemic index, glycaemic load and carbohydrate counting in the management of diabetes.” Define GI and GL with cut-offs and formula, factors affecting GI with Indian foods, a GL calculation, carb choices with an example, and how the doctor matches insulin to the count.

Remember it

GI is speed, GL is speed × amount. Cut-offs 55 and 70 for GI, 10 and 20 for GL. One carb choice = 15 g.